Granted / issued

Issued patents.

The patent records below show the inventor, assignee, filing and grant dates, expiration date computed under the 20-year-from-filing rule where applicable, and a brief technical description. The Cambridge Medical Technologies family — beginning with the 9,451,913 transdermal sampling device patent and extending through the recent 12,201,422 method-of-manufacture patent — covers the company's core non-invasive electrochemical biosensor product line and protects the clasp-product manufacturing process explicitly.

US 12,201,422 B2 View on Google Patents →

Methods of Manufacture to Optimize Performance of Transdermal Sampling and Analysis Device

Granted
January 21, 2025
Filed
December 21, 2020
Expires
December 21, 2040
Assignee
Cambridge Medical Technologies LLC

Discloses methods used to fabricate CMT's thin-film, multi-layer transdermal devices. Protects the manufacturing method used for the clasp product. One independent and three dependent claims.

US 11,633,129 B2 View on Google Patents →

Non-Invasive Transdermal Sampling and Analysis Device Incorporating Redox Cofactors

Granted
2023
Filed
April 2, 2020
Expires
April 2, 2040
Assignee
Cambridge Medical Technologies LLC

Protects the design and reduction to practice of incorporating cofactors of enzymatic reactions into working electrode hydrogels, broadening the range of biochemical assays addressable by the device. Four independent and sixteen dependent claims.

US 11,375,931 B2 View on Google Patents →

Non-Invasive Transdermal Sampling and Analysis Device Incorporating an Electrochemical Bioassay

Granted
2022
Filed
June 13, 2020
Expires
June 13, 2040
Assignee
Cambridge Medical Technologies LLC

Protects the method by which antibodies are used in the device architecture to perform direct, indirect, sandwich, or competitive bioassays such as ELISA, expanding biochemical assay capability. Three independent and seventeen dependent claims.

US 10,898,116 B2 View on Google Patents →

Methods of Manufacture to Optimize Performance of Transdermal Sampling and Analysis Device

Granted
2021
Filed
March 13, 2014
Expires
March 13, 2034
Assignee
Cambridge Medical Technologies LLC

Discloses original fabrication details for thin-film, multi-layer transdermal devices, including the method used in the clasp product. Four independent and nine dependent claims.

US 9,968,284 B2 View on Google Patents →

Anti-interferent Barrier Layers for Non-Invasive Transdermal Sampling and Analysis Device

Granted
May 15, 2018
Filed
November 29, 2012
Expires
November 29, 2032
Assignee
Clinitech, LLC

Protects the hydrogel polymer pair used on the working electrode of the clasp product, addressing electrochemical interference in transdermal sampling. Two independent and seventeen dependent claims.

US 9,877,673 B2 View on Google Patents →

Transdermal Sampling and Analysis Device

Granted
January 30, 2018
Filed
June 14, 2012
Expires
June 14, 2032
Assignee
Clinitech, LLC

Continuation with additional design specifics on the disruption mechanism, microfluidics, and electrochemical electrode geometries. Two independent and sixty-seven dependent claims.

US 9,451,913 B2 View on Google Patents →

Transdermal Sampling and Analysis Device

Granted
September 27, 2016
Filed
September 11, 2012
Expires
September 11, 2032
Assignee
Touchtek Labs, LLC

Adds novel microfluidic designs for maximal interstitial-fluid collection volume; declares geometries and dimension/property ranges covering electrical, electrochemical, and fluid-mechanical operations. Three independent and twenty dependent claims.

US 9,332,937 B2 View on Google Patents →

Systems and Methods for Monitoring Health and Delivering Drugs Transdermally

Granted
May 10, 2016
Filed
September 25, 2013
Expires
approx. 2033
Assignee
Georgetown University

Transdermal sampling system comprising at least one sampler for retrieving and transferring analyte from the skin and at least one detector for quantification.

US 8,364,228 B2 View on Google Patents →

Apparatus and Method for Continuous Real-Time Trace Biomolecular Sampling, Analysis, and Delivery

Granted
January 29, 2013
Filed
December 9, 2005
Expires
approx. 2025
Assignee
Flexible Medical Systems LLC

Transdermal sampling using sample electrodes adapted to provide voltage pulses that create capillary openings in the stratum corneum.

US 8,333,874 B2 View on Google Patents →

Flexible Apparatus and Method for Monitoring and Delivery

Granted
December 18, 2012
Filed
June 14, 2006
Expires
approx. 2026
Assignee
Flexible Medical Systems, LLC

Small, flexible, configurable system co-locating multi-level substrate sampling, rapid analysis, bio-sample storage, and delivery for living tissues.

US 7,328,105 B1 View on Google Patents →

Electronic Compass and Related Heading Filter Method

Granted
February 5, 2008
Filed
May 4, 2005
Expires
approx. 2025
Assignee
Yazaki North America, Inc.

Method for determining compass heading while reducing magnetic-noise influence by evaluating changes between magnetic-field and heading parameters.

US 6,270,651 B1 View on Google Patents →

Gas Component Sensor

Granted
August 7, 2001
Filed
February 4, 2000
Expires
approx. 2020 (expired)
Assignee
Abetif Essalik / collaborators

Electrolyte composition in bulk, thick-film, and sputtered thin-film form for a highly stable gas-component concentration sensor.

Field Effect Devices (Interface and Bandgap Engineered FET)

Granted
November 16, 1999
Filed
October 12, 1993
Expires
expired
Assignee
La Corporation de l'École Polytechnique

FET device with a first-portion channel adjacent to the source having a higher bandgap energy or electron affinity than the remaining channel, intensifying the quasi-electric field near the source and accelerating carriers.

Implantable Medication Dispensing Device

Granted
November 22, 1994
Filed
March 17, 1993
Expires
expired
Assignee
La Corporation de l'École Polytechnique

Implantable device with multiple compartments containing medicine doses, each sealed by a rupturable membrane permitting controlled dispensing.

Optical Waveguide Device and Method for Making Such Device

Granted
January 14, 1992
Filed
October 1, 1990
Expires
expired
Assignee
École Polytechnique

Optical waveguide device with refractive index higher than the substrate, plus first and second optical mirrors, with a method of fabrication.

Pending

Pending applications.

Currently pending applications extend the multi-analyte architecture — a plurality of working electrodes each prepared with selectively-coated chemistry, enabling simultaneous assay of multiple target biomolecules from a single ISF sample — into US continuation-in-part, PCT national-phase entries in China and India, and a European counterpart. These applications substantially broaden configurable biochemical assay panels available on the CMT device platform.

U.S. CIP Application No. 18/594,175 · Pub. No. US 2024/0245323 A1 View on Google Patents →

Non-Invasive Transdermal Sampling and Analysis Device for Detection of Multiple Analytes

Filed
March 4, 2024
Published
July 25, 2024
Expires
March 4, 2044
Assignee
Cambridge Medical Technologies LLC

Protects design and reduction to practice of a plurality of working electrodes — each prepared with a different selective coating — so a single ISF sample can be assayed simultaneously for multiple target biomolecules, substantially expanding configurable panels. One independent and 19 dependent claims.

U.S. Application No. 16/803,817 · Pub. No. US 2021/0267501 A1 View on Google Patents →

Non-Invasive Transdermal Sampling and Analysis Device for Detection of Multiple Analytes

Filed
February 27, 2020
Published
September 2, 2021
Expires
February 27, 2040
Assignee
Cambridge Medical Technologies LLC

Parent application establishing the multi-analyte working-electrode architecture for simultaneous ISF assay.

WO PCT Application US16/803,817 · Pub. No. WO 2021/173210 A1 View on Google Patents →

Non-Invasive Transdermal Sampling and Analysis Device for Detection of Multiple Analytes (International)

Filed
February 27, 2020
Published
September 2, 2021
Expires
February 27, 2040
Assignee
Cambridge Medical Technologies LLC

PCT counterpart with national-phase entries: China (Application 202080097449.8, published Nov 11, 2022) and India (Application 202217054644.0, published Jul 21, 2023).

Non-invasive Transdermal Sampling and Analysis Device for Detection of Multiple Analytes (Europe)

Filed
March 4, 2025
Published
September 10, 2025
Assignee
Cambridge Medical Technologies LLC

European counterpart of the multi-analyte transdermal sampling family.

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